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Human VEGF-C Quantikine ELISA Kit
R&D Systems, Inc. a Bio-Techne Brand
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Key Product Details
| Assay Length: | 4.5 hours |
| Sample Type & Volume Required Per Well: | Cell Culture Supernates (50 uL), Serum (10 uL), EDTA Plasma (50 uL), Platelet-poor Plasma (50 uL), Heparin Plasma (50 uL), Saliva (50 uL) |
| Sample Types: | Cell Culture Supernates, Serum, EDTA Plasma, Platelet-poor Plasma, Heparin Plasma, Saliva |
| Sensitivity: | 48.4 pg/mL |
| Assay Range: | 109 - 7,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Platelet-poor Plasma, Heparin Plasma, Saliva) |
| Human VEGF-C Quantikine ELISA Kit Summary: | The Quantikine Human VEGF-C Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human VEGF-C in cell culture supernates, serum, plasma, and saliva. It contains NS0-expressed recombinant human VEGF-C (Cys156Ser substituted) and has been shown to accurately quantitate the recombinant factor. Results obtained using recombinant human VEGF-C (wild type) and natural human VEGF-C showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human VEGF-C. |
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Linearity
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Human VEGF-C ELISA Cell Culture Supernate/Saliva Standard Curve |
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Human VEGF-C ELISA Serum/Plasma Standard Curve |
Citations for Human VEGF-C Quantikine ELISA Kit (49)
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Citations are publications that use Bio-Techne products. Selected citations for Human VEGF-C Quantikine ELISA Kit include:
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Species: Human
Sample Types: Cell Culture Supernates
IS Miller et al. (2022-01-01), Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects Cancer Medicine, 0(0).
PMID: 35434898 -
Species: Human
Sample Types: Cell Culture Supernates
Y Li et al. (2022-01-01), CCT5 induces epithelial-mesenchymal transition to promote gastric cancer lymph node metastasis by activating the Wnt/beta-catenin signalling pathway British Journal of Cancer, 0(0).
PMID: 35194191 -
Species: Human
Sample Types: Cell Culture Supernates
S Biswas Shi et al. (2022-01-01), Platelet-derived growth factor BB is reduced in endometrial endothelial cells of women with abnormal uterine bleeding-endometrial disorder Oncogene, 0(0).
PMID: 35739007 -
Species: Human
Sample Types: Cell Lysates
J Suzuki et al. (2022-01-01), Hydrogen Sulfide Attenuates Lymphedema Via the Induction of Lymphangiogenesis Through a PI3K/Akt-Dependent Mechanism Journal of the American Heart Association, 11(21):e026889.
PMID: 36285798 -
Species: Human
Sample Types: Cell Lysates
J Zhong et al. (2022-01-01), Dicarbonyl-modified lipoproteins contribute to proteinuric kidney injury JCI Insight, 7(21).
PMID: 36125905 -
Species: Human
Sample Types: Serum
M Sevinc et al. (2021-01-01), Comparison of lung ultrasound and other volumetric methods in peritoneal dialysis patients Medicine, 100(3):e23856.
PMID: 33545952 -
Species: Mouse
Sample Types: Plasma
T Mashima et al. (2021-01-01), Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo Scientific Reports, 11(1):15125.
PMID: 34302038 -
Species: Human
Sample Types: Vitreous Humor
I Wada et al. (2021-01-01), Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1+ Macrophage Infiltration Investigative Ophthalmology Visual Science, 2021;62(13):17.
PMID: 34673901 -
Species: Human
Sample Types: Cell Lysates
C Reglero et al. (2020-01-01), GRK2-Dependent HuR Phosphorylation Regulates HIF1&alpha Activation under Hypoxia or Adrenergic Stress Cancers (Basel), 12(5).
PMID: 32413989 -
Species: Human
Sample Types: Serum
AZ Dudek et al. (2020-01-01), Phase Ib/II Clinical Trial of Pembrolizumab With Bevacizumab for Metastatic Renal Cell Carcinoma: BTCRC-GU14-003 J. Clin. Oncol., 38(11):1138-1145.
PMID: 32097091 -
Species: Human
Sample Types: Serum
WN Li et al. (2020-01-01), Extracellular vesicle-associated VEGF-C promotes lymphangiogenesis and immune cells infiltration in endometriosis Proc Natl Acad Sci U S A, 0(0).
PMID: 33004630 -
Species: Human
Sample Types: Serum
H Wada et al. (2020-01-01), Distinct Characteristics of VEGF-D and VEGF-C to Predict Mortality in Patients With Suspected or Known Coronary Artery Disease J Am Heart Assoc, 9(9):e015761.
PMID: 32319336 -
Species: Human
Sample Types: Cell Culture Supernates
R Wang et al. (2019-01-01), Distribution and Activity of Lenvatinib in Brain Tumor Models of Human Anaplastic Thyroid Cancer Cells in Severe Combined Immune Deficient Mice Mol. Cancer Ther., 18(5):947-956.
PMID: 30926637 -
Species: Human
Sample Types: Seminal Plasma
SK Jha et al. (2019-01-01), KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D Elife, 8(0).
PMID: 31099754 -
Species: Mouse
Sample Types: Tissue Homogenates
AR Harris et al. (2018-01-01), Docetaxel facilitates lymphatic-tumor crosstalk to promote lymphangiogenesis and cancer progression BMC Cancer, 18(1):718.
PMID: 29976154 -
Species: Human
Sample Types: Cell Culture Supernates
CZ Li et al. (2018-01-01), RIP1 regulates TNF-?-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-?B-VEGF-C pathway Onco Targets Ther, 11(0):2875-2890.
PMID: 29844685 -
Species: Mouse
Sample Types: Serum
S Schwager et al. (2018-01-01), Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation JCI Insight, 3(23).
PMID: 30518687 -
Species: Human
Sample Types: Cell Culture Supernates
X Jiang et al. (2017-01-01), cIAP2 promotes gallbladder cancer invasion and lymphangiogenesis by activating the NF-?B pathway Cancer Sci., 108(6):1144-1156.
PMID: 28295868 -
Species: Human
Sample Types: Cell Culture Supernates
Débora C Bastos (2016-01-01), Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model Lab. Invest, 0(0).
PMID: 27918556 -
Species: Human
Sample Types: Plasma
David M Briscoe (2016-01-01), Vascular endothelial growth factor A is associated with the subsequent development of moderate or severe cardiac allograft vasculopathy in pediatric heart transplant recipients J. Heart Lung Transplant., 0(0).
PMID: 27865734 -
Species: Human
Sample Types: Cell Culture Supernates
(2016-01-01), Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling Sci Rep, 6(0):29029.
PMID: 27374240 -
Species: Human
Sample Types: Cell Culture Supernates
Tokumoto M et al. (2015-01-01), Identification of tumour-reactive lymphatic endothelial cells capable of inducing progression of gastric cancer. Br J Cancer, 113(7):1046-54.
PMID: 26355233 -
Species: Human
Sample Types: Cell Culture Supernates
Tutunea-Fatan et al. (2015-01-01), The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis. Mol Cancer, 14(1):35.
PMID: 25744065 -
Species: Human
Sample Types: Cell Culture Supernates
Yang M et al. (2014-01-01), KML001 inhibits cell proliferation and invasion in pancreatic cancer cells through suppression of NF-kappaB and VEGF-C. Anticancer Res, 34(7):3469-74.
PMID: 24982355 -
Species: Human
Sample Types: Cell Culture Supernates
Weinkopff T et al. (2014-01-01), Filarial excretory-secretory products induce human monocytes to produce lymphangiogenic mediators. PLoS Negl Trop Dis, 8(7):e2893.
PMID: 25010672 -
Species: Human
Sample Types: Serum
Sallinen H et al. (2014-01-01), Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer. BMC Cancer, 14(0):696.
PMID: 25245329 -
Species: Human
Sample Types: Ascites Fluid
Decio A et al. (2014-01-01), Vascular endothelial growth factor c promotes ovarian carcinoma progression through paracrine and autocrine mechanisms. Am J Pathol, 184(4):1050-61.
PMID: 24508126 -
Species: Human
Sample Types: Cell Culture Supernates
Kimura H et al. (2014-01-01), Telmisartan, a possible PPAR-delta agonist, reduces TNF-alpha-stimulated VEGF-C production by inhibiting the p38MAPK/HSP27 pathway in human proximal renal tubular cells. Biochem Biophys Res Commun, 454(2):320-7.
PMID: 25450396 -
Species: Human
Sample Types: Serum
Braicu E et al. (2013-01-01), Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin and paclitaxel containing sequential radiotherapy. Cytokine, 61(3):755-8.
PMID: 23415672 -
Species: Human
Sample Types: Plasma
Armstrong A et al. (2013-01-01), Long-term survival and biomarker correlates of tasquinimod efficacy in a multicenter randomized study of men with minimally symptomatic metastatic castration-resistant prostate cancer. Clin Cancer Res, 19(24):6891-901.
PMID: 24255071 -
Species: Human
Sample Types: Cell Culture Supernates
Yazdani S et al. (2012-01-01), Proteinuria triggers renal lymphangiogenesis prior to the development of interstitial fibrosis. PLoS ONE, 7(11):e50209.
PMID: 23189189 -
Species: Human
Sample Types: Cell Culture Supernates
Majumder M et al. (2012-01-01), Co-expression of alpha9beta1 integrin and VEGF-D confers lymphatic metastatic ability to a human breast cancer cell line MDA-MB-468LN. PLoS ONE, 7(4):e35094.
PMID: 22545097 -
Species: Human
Sample Types: Cell Culture Supernates
Lin CE et al. (2012-01-01), Lysophosphatidic Acid Enhances Vascular Endothelial Growth Factor-C Expression in Human Prostate Cancer PC-3 Cells. PLoS ONE, 7(7):e41096.
PMID: 22911748 -
Species: Human
Sample Types: Serum
Landt S et al. (2011-01-01), Prognostic significance of angiogenic factors in uterine cervical cancer. Anticancer Res., 31(8):2589-95.
PMID: 21778309 -
Species: Human
Sample Types: Plasma
Harmon CS et al. (2011-01-01), Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib. J Transl Med, 9(0):120.
PMID: 21787417 -
Species: Human
Sample Types: Cell Culture Supernates
Scheel C et al. (2011-01-01), Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell, 145(6):926-40.
PMID: 21663795 -
Species: Human
Sample Types: Serum
Konings IR et al. (2010-01-01), Phase I and pharmacological study of the broad-spectrum tyrosine kinase inhibitor JNJ-26483327 in patients with advanced solid tumours. Br. J. Cancer, 103(7):987-92.
PMID: 20823884 -
Species: Human
Sample Types: Cell Culture Supernates
Ha CT et al. (2010-01-01), Human pregnancy specific beta-1-glycoprotein 1 (PSG1) has a potential role in placental vascular morphogenesis. Biol. Reprod., 83(1):27-35.
PMID: 20335639 -
Species: Human
Sample Types: Serum
Machnik A et al. (2009-01-01), Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat. Med., 15(5):545-52.
PMID: 19412173 -
Species: Human
Sample Types: Plasma
Zhu AX et al. (2009-01-01), Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study. J. Clin. Oncol., 27(18):3027-35.
PMID: 19470923 -
Species: Human
Sample Types: Serum
Onimaru M et al. (2009-01-01), VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B. Am. J. Physiol. Heart Circ. Physiol., 297(5):H1685-96.
PMID: 19734356 -
Species: Human
Sample Types: Serum
Huang V et al. (2008-01-01), Cutting edge: rapid accumulation of epidermal CCL27 in skin-draining lymph nodes following topical application of a contact sensitizer recruits CCR10-expressing T cells. J. Immunol., 180(10):6462-6.
PMID: 18453562 -
Species: Human
Sample Types: Cell Culture Supernates
Sorrentino A et al. (2008-01-01), Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp. Hematol., 36(8):1035-46.
PMID: 18504067 -
Species: Human
Sample Types: Plasma
Rini BI et al. (2008-01-01), Antitumor activity and biomarker analysis of sunitinib in patients with bevacizumab-refractory metastatic renal cell carcinoma. J. Clin. Oncol., 26(22):3743-8.
PMID: 18669461 -
Species: Human
Sample Types: Cell Culture Supernates
Simiantonaki N et al. (2008-01-01), Hypoxia-induced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines. Int. J. Oncol., 32(3):585-92.
PMID: 18292935 -
Species: Human
Sample Types: Cell Culture Supernates
Riccioni R et al. (2007-01-01), Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts. Stem Cells, 25(8):1862-71.
PMID: 17446561 -
Species: Human
Sample Types: Plasma
Lee CY et al. (2007-01-01), Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia. Br. J. Cancer, 97(7):877-82.
PMID: 17848952 -
Species: Human
Sample Types: Cell Culture Supernates
Laakkonen P et al. (2007-01-01), Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth. Cancer Res., 67(2):593-9.
PMID: 17234768 -
Species: Human
Sample Types: Tissue Homogenates
Lin J et al. (2005-01-01), Inhibition of lymphogenous metastasis using adeno-associated virus-mediated gene transfer of a soluble VEGFR-3 decoy receptor. Cancer Res., 65(15):6901-9.
PMID: 16061674
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Customer Reviews for Human VEGF-C Quantikine ELISA Kit (3)
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Sample Tested: HeLa cellsVerified Customer | Posted 08/26/2020
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Sample Tested: Human cell conditioned medium,Mouse cell conditioned mediumVerified Customer | Posted 12/12/2019Works for mouse samples
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Sample Tested: 7TD1 mouse hybridoma cell lineVerified Customer | Posted 10/17/2019
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Product Documents for Human VEGF-C Quantikine ELISA Kit
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.
