Human Phospho-p70 S6 Kinase (T389) DuoSet IC ELISA
R&D Systems, part of Bio-Techne | Catalog # DYC896B-2
Product Specifications
Detection Method
Colorimetric ELISA - 450nm (TMB)
Specificity
Label
HRP
Preparation and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: p70 S6 Kinase
p70 S6 kinase is a Ser/Thr kinase activated by such mitogens as EGF, IGF-I, and insulin. The S6 protein of the 40S ribosomal subunit is a major substrate of p70 S6 kinase, and its phosphorylation upregulates the translation of mRNAs containing an oligopyrimidine tract at their transcriptional start site. The activity of p70 S6 kinase is controlled by multiple phosphorylation events, with phosphorylation at T229 by PDK1 and T389 by mTOR most critical for kinase function.
Alternate Names
p70-alpha, RPS6KB1, S6K1, STK14A
Gene Symbol
RPS6KB1
Additional p70 S6 Kinase Products
Product Documents for Human Phospho-p70 S6 Kinase (T389) DuoSet IC ELISA
Product Specific Notices for Human Phospho-p70 S6 Kinase (T389) DuoSet IC ELISA
For research use only
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