Human IGFBP-3 Quantikine ELISA Kit
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Assay Length: | 4.5 hours |
Sample Type & Volume Required Per Well: | Cell Culture Supernates (100 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL) |
Sample Types: | Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma |
Sensitivity: | 0.14 ng/mL |
Assay Range: | 0.781 - 50 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Human IGFBP-3 Quantikine ELISA Kit Summary: | The Quantikine Human IGFBP-3 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human IGFBP-3 in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human IGFBP-3 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human IGFBP-3 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human IGFBP-3. |
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Citations for Human IGFBP-3 Quantikine ELISA Kit (42)
Citations are publications that use Bio-Techne products. Selected citations for Human IGFBP-3 Quantikine ELISA Kit include:
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Species: Human
Sample Types: Serum
JA Goldsmith et al. (2022-01-01), Visceral Adiposity, Inflammation, and Testosterone Predict Skeletal Muscle Mitochondrial Mass and Activity in Chronic Spinal Cord Injury Frontiers in Physiology, 13(0):809845.
PMID: 35222077 -
Species: Human
Sample Types: Conditioned Media
WL Stuard et al. (2022-01-01), IGFBP-3 Regulates Mitochondrial Hyperfusion and Metabolic Activity in Ocular Surface Epithelia during Hyperosmolar Stress International Journal of Molecular Sciences, 23(7).
PMID: 35409425 -
Species: Human
Sample Types: Plasma
MK ?widerska et al. (2022-01-01), Energy Homeostasis Gene Nucleotide Variants and Survival of Hemodialysis Patients-A Genetic Cohort Study Journal of Clinical Medicine, 11(18).
PMID: 36143124 -
Species: Human
Sample Types: Cell Lysates
ED Bogdan et al. (2021-01-01), IGFBP-3 Mediates Metabolic Homeostasis During Hyperosmolar Stress in the Corneal Epithelium Investigative Ophthalmology Visual Science, 2021;62(7):11.
PMID: 34100890 -
Species: Human
Sample Types: Serum
J Yang et al. (2021-01-01), Discovery and validation of PZP as a novel serum biomarker for screening lung adenocarcinoma in type 2 diabetes mellitus patients Cancer Cell International, 21(1):162.
PMID: 33691685 -
Species: Human
Sample Types: Serum
F Buckinx et al. (2020-01-01), High intensity interval training combined with L-citrulline supplementation: Effects on physical performance in healthy older adults Exp. Gerontol., 0(0):111036.
PMID: 32721549 -
Species: Human
Sample Types: Plasma
Z Zeng et al. (2020-01-01), PM2.5-bound PAHs exposure linked with low plasma insulin-like growth factor 1 levels and reduced child height Environ Int, 138(0):105660.
PMID: 32199227 -
Species: Human
Sample Types: Plasma
KR Monson et al. (2020-01-01), Circulating growth factor concentrations and breast cancer risk: a nested case-control study of IGF-1, IGFBP-3, and breast cancer in a family-based cohort Breast Cancer Res, 22(1):109.
PMID: 33092613 -
Species: Human
Sample Types: Plasma
J Sakata et al. (2020-01-01), Enhanced Expression of IGFBP-3 Reduces Radiosensitivity and Is Associated with Poor Prognosis in Oral Squamous Cell Carcinoma Cancers (Basel), 12(2).
PMID: 32093285 -
Species: Human
Sample Types: Serum
P Fahlbusch et al. (2020-01-01), Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men Int J Mol Sci, 21(11).
PMID: 32532003 -
Species: Human
Sample Types: Plasma
RH Bartels et al. (2019-01-01), Hypoallergenic and anti-inflammatory feeds in children with complicated severe acute malnutrition: an open randomised controlled 3-arm intervention trial in Malawi Sci Rep, 9(1):2304.
PMID: 30783173 -
Species: Human
Sample Types: Plasma
A Malin Igra et al. (2019-01-01), Early-Life Cadmium Exposure and Bone-Related Biomarkers: A Longitudinal Study in Children Environ. Health Perspect., 127(3):37003.
PMID: 30848671 -
Species: Human
Sample Types: Plasma
M Krause et al. (2018-01-01), The effects of a combined bodyweight-based and elastic bands resistance training, with or without protein supplementation, on muscle mass, signaling and heat shock response in healthy older people Exp. Gerontol., 115(0):104-113.
PMID: 30529477 -
Species: Human
Sample Types: Serum
MD DeBoer et al. (2018-01-01), Increases in IGF-1 after Anti-TNF-? Therapy are Associated with Bone and Muscle Accrual in Pediatric Crohn's Disease J. Clin. Endocrinol. Metab., 0(0).
PMID: 29329430 -
Species: Human
Sample Types: Cell Culture Supernates
Ge Sheng Cheng (2017-01-01), Bone marrow-derived mesenchymal stem cells modified with IGFBP-3 inhibit the proliferation of pulmonary artery smooth muscle cells Int. J. Mol. Med, 39(1):223-230.
PMID: 27959432 -
Species: Human
Sample Types: Plasma
G Annibalini et al. (2017-01-01), Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients Oxid Med Cell Longev, 2017(0):3937842.
PMID: 28713486 -
Species: Human
Sample Types: Plasma
A Olszanecka et al. (2017-01-01), Relationships of insulin-like growth factor-1, its binding proteins, and cardiometabolic risk in hypertensive perimenopausal women Metab. Clin. Exp., 69(0):96-106.
PMID: 28285656 -
Species: Human
Sample Types: Serum
JR Gee et al. (2017-01-01), A phase II randomized, double-blind, presurgical trial of Polyphenon E in bladder cancer patients to evaluate pharmacodynamics and bladder tissue biomarkers Cancer Prev Res (Phila), 0(0).
PMID: 28325826 -
Species: Human
Sample Types: Cell Culture Supernates
S Sakimoto et al. (2017-01-01), CD44 expression in endothelial colony-forming cells regulates neurovascular trophic effect JCI Insight, 2(2):e89906.
PMID: 28138561 -
Species: Human
Sample Types: Serum
(2016-01-01), The Differential Hormonal Milieu of Morning versus Evening May Have an Impact on Muscle Hypertrophic Potential PLoS ONE, 11(9):e0161500.
PMID: 27583459 -
Species: Human
Sample Types: Serum
Howard H Bailey (2016-01-01), Phase IIa, randomized placebo-controlled trial of single high dose cholecalciferol (vitamin D3) and daily Genistein (G-2535) versus double placebo in men with early stage prostate cancer undergoing prostatectomy Am J Clin Exp Urol, 4(2):17-27.
PMID: 27766277 -
Species: Human
Sample Types: CSF
Matthew N Svalina (2016-01-01), IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma Sci Rep, 6(0):27012.
PMID: 27255663 -
Species: Human
Sample Types: Serum
(2016-01-01), Genetic variation in IGF1 predicts renal cell carcinoma susceptibility and prognosis in Chinese population Sci Rep, 6(0):39014.
PMID: 27976731 -
Species: Human
Sample Types: Serum
Applications: ELISA CaptureMatthew P Rowan et al. (2016-01-01), Elevations in growth hormone and glucagon-like peptide-2 levels on admission are associated with increased mortality in trauma patients. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 0(0):1757-7241.
PMID: 27716276 -
Species: Human
Sample Types: Serum
Kim H et al. (2015-01-01), Effects of exercise and milk fat globule membrane (MFGM) supplementation on body composition, physical function, and hematological parameters in community-dwelling frail Japanese women: a randomized double blind, placebo-controlled, follow-up trial. PLoS ONE, 10(2):e0116256.
PMID: 25659147 -
Species: Human
Sample Types: Serum
Nguyen K et al. (2015-01-01), Glucose intolerance in aging male IGFBP-3 transgenic mice: differential effects of human IGFBP-3 and its mutant IGFBP-3 devoid of IGF binding ability. Endocrinology, 156(2):462-74.
PMID: 25490144 -
Species: Human
Sample Types: Cell Culture Supernates
Choi Y et al. (2013-01-01), Role of IGF-binding protein 3 in the resistance of EGFR mutant lung cancer cells to EGFR-tyrosine kinase inhibitors. PLoS ONE, 8(12):e81393.
PMID: 24339922 -
Species: Human
Sample Types: Serum
Braicu E et al. (2013-01-01), Role of serum concentration of VEGFR1 and TIMP2 on clinical outcome in primary cervical cancer: results of a companion protocol of the randomized, NOGGO-AGO phase III adjuvant trial of simultaneous cisplatin-based radiochemotherapy vs. carboplatin and paclitaxel containing sequential radiotherapy. Cytokine, 61(3):755-8.
PMID: 23415672 -
Species: Human
Sample Types: Cell Culture Supernates
Imamura et al. (2012-01-01), FOXA1 promotes tumor progression in prostate cancer via the insulin-like growth factor binding protein 3 pathway. PLoS ONE, 7(8):e42456.
PMID: 22879989 -
Species: Human
Sample Types: Cell Culture Supernates
Weimer A et al. (2012-01-01), Benefits of recombinant adeno-associated virus (rAAV)-mediated insulinlike growth factor I (IGF-I) overexpression for the long-term reconstruction of human osteoarthritic cartilage by modulation of the IGF-I axis. Mol. Med., 18(1):346-58.
PMID: 22160392 -
Species: Human
Sample Types: Serum
(2012-01-01), Administration of omega-3 fatty acids and Raloxifene to women at high risk of breast cancer: interim feasibility and biomarkers analysis from a clinical trial. Eur J Clin Nutr, 66(8):878-84.
PMID: 22669332 -
Species: Human
Sample Types: Plasma
Higgins MF et al. (2012-01-01), Maternal and fetal placental growth hormone and IGF axis in type 1 diabetic pregnancy. PLoS ONE, 7(2):e29164.
PMID: 22363400 -
Species: Human
Sample Types: Cell Culture Supernates
Elzi et al. (2012-01-01), Plasminogen activator inhibitor 1--insulin-like growth factor binding protein 3 cascade regulates stress-induced senescence. Proc Natl Acad Sci U S A, 109(30):12052-7.
PMID: 22778398 -
Species: Human
Sample Types: Serum
Landt S et al. (2011-01-01), Prognostic significance of angiogenic factors in uterine cervical cancer. Anticancer Res., 31(8):2589-95.
PMID: 21778309 -
Species: Human
Sample Types: Serum
Morgan K et al. (2011-01-01), The stature of boys is inversely correlated to the levels of their sertoli cell hormones: do the testes restrain the maturation of boys? PLoS ONE, 6(6):e20533.
PMID: 21655101 -
Species: Human
Sample Types: Plasma
Sesso R et al. (2010-01-01), Abnormalities in metalloproteinase pathways and IGF-I axis: a link between birth weight, hypertension, and vascular damage in childhood. Am. J. Hypertens., 23(1):6-11.
PMID: 19893495 -
Species: Human
Sample Types: Plasma
Oy GF et al. (2010-01-01), Biological effects induced by insulin-like growth factor binding protein 3 (IGFBP-3) in malignant melanoma. Int. J. Cancer, 126(2):350-61.
PMID: 19588500 -
Species: Human
Sample Types: Plasma
Akhtar S et al. (2009-01-01), Grape seed proanthocyanidins inhibit the growth of human non-small cell lung cancer xenografts by targeting insulin-like growth factor binding protein-3, tumor cell proliferation, and angiogenic factors. Clin. Cancer Res., 15(3):821-31.
PMID: 19188152 -
Species: Human
Sample Types: BALF
Veraldi KL et al. (2009-01-01), Role of insulin-like growth factor binding protein-3 in allergic airway remodeling. Am. J. Respir. Crit. Care Med., 180(7):611-7.
PMID: 19608721 -
Species: Human
Sample Types: Serum
Schoyer KD et al. (2007-01-01), Serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3) in IVF patients with polycystic ovary syndrome: correlations with outcome. Fertil. Steril., 88(1):139-44.
PMID: 17320874 -
Species: Human
Sample Types: Plasma
Yin D et al. (2007-01-01), Clinical pharmacodynamic effects of the growth hormone receptor antagonist pegvisomant: implications for cancer therapy. Clin. Cancer Res., 13(3):1000-9.
PMID: 17289896 -
Species: Human
Sample Types: Follicular Fluid
Wang TH et al. (2006-01-01), Insulin-like growth factor-II (IGF-II), IGF-binding protein-3 (IGFBP-3), and IGFBP-4 in follicular fluid are associated with oocyte maturation and embryo development. Fertil. Steril., 86(5):1392-401.
PMID: 17070193
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Customer Reviews for Human IGFBP-3 Quantikine ELISA Kit (3)
Customer Images
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Sample Tested: Human PlasmaVerified Customer | Posted 05/16/2017
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Sample Tested: Human PlasmaVerified Customer | Posted 05/16/2017
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Sample Tested: SerumVerified Customer | Posted 10/24/2016the results are stable.
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Product Documents for Human IGFBP-3 Quantikine ELISA Kit
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.