Human IFN-alpha Serum Sample ELISA Kit

Name: Human IFN-alpha Serum Sample ELISA Kit
Brand: R&D Systems
SKU: 41110-1

R&D Systems, Inc. a Bio-Techne Brand

Catalog # 41110-1

Citations (4)

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Key Product Details

Assay Length:	3.25 hours
Sample Type & Volume Required Per Well:	Cell Culture Supernates (100 uL), Serum (100 uL), Plasma (100 uL)
Sample Types:	Cell Culture Supernates, Serum, Plasma
Sensitivity:	12.5 pg/mL
Assay Range:	12.5 - 1,000 pg/mL (Cell Culture Supernates, Serum, Plasma)

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Product Specifications for Human IFN-alpha Serum Sample ELISA Kit

Measurement	Quantitative ELISA
Conjugate	Biotin
Reactivity	Human
Specificity	Human IFN-alpha
Cross-reactivity	< 0.5% cross-reactivity observed with available related molecules. < 50% cross-species reactivity observed with species tested.
Interference	No significant interference observed with available related molecules.

Preparation and Storage

Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Item	Value
Long Name	Interferon alpha
Entrez Gene IDs	3440 (Human)
Alternate Names	IFN-alpha, IFN-alphaA, IFNA, IFNA2, IFNA2b, IFNalpha, INFA2, LeIF D, interferon alpha 2

Citations for Human IFN-alpha Serum Sample ELISA Kit (4)

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Citations are publications that use Bio-Techne products. Selected citations for Human IFN-alpha Serum Sample ELISA Kit include:

Species: Human
Sample Types: Cell Culture Supernates

S Ding et al. (2018), STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection Nat Commun, 9(1):1485.
PMID: 29662124
Species: Human
Sample Types: Serum

Liu L et al. (2012), Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling. J. Biol. Chem., 287(15):11899-910.
PMID: 22343630
Species: Porcine
Sample Types: Plasma

Cheng G et al. (2007), Alpha interferon is a powerful adjuvant for a recombinant protein vaccine against foot-and-mouth disease virus in swine, and an effective stimulus of in vivo immune response. Vaccine, 25(28):5199-208.
PMID: 17555848
Species: Human
Sample Types: Serum

Yoshikawa H et al. (2006), Elevation of IL-12 p40 and its antibody in myasthenia gravis with thymoma. J. Neuroimmunol., 175(1):169-75.
PMID: 16574246

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