Human Flt-3 Ligand/FLT3L Quantikine ELISA Kit
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Assay Length: | 4 hours or 4.5 hours |
Sample Type & Volume Required Per Well: | Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL), Citrate Plasma (50 uL) |
Sample Types: | Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma |
Sensitivity: | 7 pg/mL |
Assay Range: | 15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
Human Flt-3 Ligand/FLT3L Quantikine ELISA Kit Summary: | The Quantikine Human Flt-3/Flk-2 Ligand Immunoassay is a 4.0 or 4.5 hour solid phase ELISA designed to measure soluble human Flt-3 Ligand in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human Flt-3 Ligand and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant Flt-3 Ligand accurately. Results obtained measuring natural human Flt-3 Ligand showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human Flt-3 Ligand. |
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Citations for Human Flt-3 Ligand/FLT3L Quantikine ELISA Kit (19)
Citations are publications that use Bio-Techne products. Selected citations for Human Flt-3 Ligand/FLT3L Quantikine ELISA Kit include:
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Species: Human
Sample Types: Plasma
JR Loughland et al. (2021), Reduced circulating dendritic cells in acute Plasmodium knowlesi and Plasmodium falciparum malaria despite elevated plasma Flt3 ligand levels Malaria Journal, 20(1):97.
PMID: 33593383 -
Species: Human
Sample Types: Serum
KM Detjen et al. (2021), Elevated Flt3L Predicts Long-Term Survival in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms Cancers, 13(17).
PMID: 34503273 -
Species: Human
Sample Types: Cell Culture Supernates
Y Yuan et al. (2019), HIV-1 Tat protein inhibits the hematopoietic support function of human bone marrow mesenchymal stem cells Virus Res., 273(0):197756.
PMID: 31521762 -
Species: Human
Sample Types: Cell Culture Supernates
T Kawase et al. (2019), Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Oncotarget, 10(58):6111-6123.
PMID: 31692922 -
Species: Human
Sample Types: Cell Culture Supernates
X Yuan et al. (2019), Mesenchymal stem cell therapy induces FLT3L and CD1c+ dendritic cells in systemic lupus erythematosus patients Nat Commun, 10(1):2498.
PMID: 31175312 -
Species: Human
Sample Types: Serum
E Kalanxhi et al. (2018), Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer Br. J. Cancer, 118(10):1322-1328.
PMID: 29695770 -
Species: Human
Sample Types: Cell Culture Supernates
AK Batsali et al. (2017), Differential expression of cell cycle and WNT pathway-related genes accounts for differences in the growth and differentiation potential of Wharton's jelly and bone marrow-derived mesenchymal stem cells Stem Cell Res Ther, 8(1):102.
PMID: 28446235 -
Species: Human
Sample Types: Serum
S Ciullini M et al. (2016), Timely follow-up of a GATA2 deficiency patient allows successful treatment J. Allergy Clin. Immunol, 138(5):1480-1483.e4.
PMID: 27481672 -
Species: Human
Sample Types: Cell Culture Supernates
Nguyen T et al. (2015), EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance. Stem Cells, 33(9):2838-49.
PMID: 26033476 -
Species: Human
Sample Types: Cell Culture Supernates
Xiong W et al. (2010), Human Flt3L generates dendritic cells from canine peripheral blood precursors: implications for a dog glioma clinical trial. PLoS ONE, 5(6):e11074.
PMID: 20552015 -
Species: Primate - Macaca nemestrina (Southern Pig-tailed Macaque)
Sample Types: Serum
Reeves RK et al. (2009), Systemic dendritic cell mobilization associated with administration of FLT3 ligand to SIV- and SHIV-infected macaques. AIDS Res. Hum. Retroviruses, 25(12):1313-28.
PMID: 20001520 -
Species: Human
Sample Types: Serum
Curtin JF et al. (2006), Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain. J. Immunol., 176(6):3566-77.
PMID: 16517725 -
Species: Human
Sample Types: Cell Culture Supernates
Hatfield K et al. (2006), Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts. Int. J. Cancer, 119(10):2313-21.
PMID: 16921487 -
Species: Human
Sample Types: CSF
(2006), Cerebrospinal fluid Flt3 ligand level in patients with amyotrophic lateral sclerosis. Acta Neurol. Scand., 114(3):205-9.
PMID: 16911350 -
Drouet M et al. (2004), Single administration of stem cell factor, FLT-3 ligand, megakaryocyte growth and development factor, and interleukin-3 in combination soon after irradiation prevents nonhuman primates from myelosuppression: long-term follow-up of hematopoiesis. Blood, 103(3):878-85.
PMID: 14525791 -
Species: Human
Sample Types: Tissue Homogenates
Ali S et al. (2004), Inflammatory and anti-glioma effects of an adenovirus expressing human soluble Fms-like tyrosine kinase 3 ligand (hsFlt3L): treatment with hsFlt3L inhibits intracranial glioma progression. Mol. Ther., 10(6):1071-84.
PMID: 15564139 -
Species: Human
Sample Types: Cell Culture Supernates
Briard D et al. (2002), Fibroblasts from human spleen regulate NK cell differentiation from blood CD34(+) progenitors via cell surface IL-15. J. Immunol., 168(9):4326-32.
PMID: 11970974 -
Species: Human
Sample Types: Cell Culture Supernates
Loeuillet C et al. (2001), Distinct hematopoietic support by two human stromal cell lines. Exp. Hematol., 29(6):736-45.
PMID: 11378269 -
Species: Human
Sample Types: Cell Culture Supernates
Solanilla A et al. (2000), CD40-ligand stimulates myelopoiesis by regulating flt3-ligand and thrombopoietin production in bone marrow stromal cells. Blood, 95(12):3758-64.
PMID: 10845907
There are no citations that match your criteria.
Customer Reviews for Human Flt-3 Ligand/FLT3L Quantikine ELISA Kit (3)
Customer Images
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Sample Tested: Murine mesenteric lymph nodeVerified Customer | Posted 07/12/2018
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Sample Tested: CHO Chinese hamster ovary cell lineVerified Customer | Posted 12/21/2017
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Sample Tested: Normal human serum samplesVerified Customer | Posted 12/07/2017ELISA detected all tested human normal serum samples with range of 54 to 111 pg/mL.
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Product Documents for Human Flt-3 Ligand/FLT3L Quantikine ELISA Kit
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.