Human CCL21/6Ckine Quantikine ELISA Kit
R&D Systems, part of Bio-Techne | Catalog # D6C00
Discontinued Product
D6C00 has been discontinued.
View all CCL21/6Ckine products.
Key Product Details
Sensitivity
33.5 pg/mL
Assay Range
78.1-5000 pg/mL
Product Specifications
Measurement
Quantitative ELISA
Detection Method
Colorimetric - 450nm (TMB)
Reactivity
Human
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules. < 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.
Linearity
Preparation and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: CCL21/6Ckine
CCL21, also known as 6Ckine, TCA-4, SLC, Exodus-2, and A21, is a homeostatic chemokine that signals through CCR7 or CXCR3. CCL21 is constitutively presented on initial lymphatic vessels, high endothelial venules (HEV), and lymph node dendritic cells (DC) where it promotes the docking of DC to lymphatic vessels and the retention of T cells by lymph node DC, resulting in T cell priming for activation. Its upregulation during chronic inflammation or tissue damage promotes fibrosis, inflammatory cytokine production, and neuropathic pain. The soluble chemokine is elevated in rheumatoid arthritis synovial fluid and in the serum of coronary artery disease patients.
Alternate Names
6Ckine, exodus-2, SCYA21, SLC, TCA-4
Gene Symbol
CCL21
Additional CCL21/6Ckine Products
Product Documents for Human CCL21/6Ckine Quantikine ELISA Kit
Product Specific Notices for Human CCL21/6Ckine Quantikine ELISA Kit
For research use only
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