Mouse NKp46/NCR1 (AAI15365) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC2170
Key Product Details
Species
Mouse
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: NKp46/NCR1
NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.
Alternate Names
CD335, Ly94, MAR-1, NCR1
Gene Symbol
NCR1
UniProt
Additional NKp46/NCR1 Products
Product Documents for Mouse NKp46/NCR1 (AAI15365) VersaClone cDNA
Product Specific Notices for Mouse NKp46/NCR1 (AAI15365) VersaClone cDNA
For research use only
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