Mouse IL-17B (NP_062381.1) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3717
Key Product Details
Species
Mouse
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IL-17B
Interleukin-17B is an approximately 20 kDa glycosylated cytokine that plays a role in inflammation and bone growth. IL-17B binds to IL-17 RB and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells. It is expressed in the central nervous system, testis, ovary, stomach, pancreas, and small intestine. In the skeletal system, IL-17B is expressed in bone collars surrounding primary ossification centers as well as in epiphyseal plate chondrocytes during development and after bone fracture. IL-17B is upregulated in arthritic cartilage where it exacerbates the severity of disease. It is also upregulated in aggressive breast cancer cell lines, and its exaggerated signaling through IL-17 RB promotes tumorigenicity.
Long Name
Interleukin 17B
Alternate Names
IL17B
Gene Symbol
IL17B
UniProt
Additional IL-17B Products
Product Documents for Mouse IL-17B (NP_062381.1) VersaClone cDNA
Product Specific Notices for Mouse IL-17B (NP_062381.1) VersaClone cDNA
For research use only
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