Mouse CD200R1 (NP_067300) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC2084
Key Product Details
Species
Mouse
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: CD200R1
CD200 antigen, also known as OX-2, is a type I transmembrane protein belonging to the Ig superfamily. It has a 202 amino acid extracellular domain and a short (19 aa) cytoplasmic tail. At least two alternate splice isoforms exist that differ in their cytoplasmic domains. CD200 is widely expressed in multiple cell types. It interacts with CD200R1, another Ig superfamily inhibitory receptor primarily expressed on leukocytes of the myeloid lineage, to inhibit myeloid functions.
CD200R1, also known as OX-2 receptor, is a transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed primarily in cells of the myeloid lineage, while its ligand, CD200, is widely distributed. CD200R1 is though to propagate inhibitory signals and disruption of the CD200/CD200R1 receptor-ligand pair leads to a predisposition to autoimmune phenotypes.
Long Name
CD200 Receptor 1
Alternate Names
CD200 R1, MOX2R
Gene Symbol
CD200R1
UniProt
Additional CD200R1 Products
Product Documents for Mouse CD200R1 (NP_067300) VersaClone cDNA
Product Specific Notices for Mouse CD200R1 (NP_067300) VersaClone cDNA
For research use only
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