Human TDP-43/TARDBP (NP_031401.1) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC3308

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Key Product Details

Species

Human

Accession Number

NP_031401.1

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: TDP-43/TARDBP

TARDBP, also known as TAR DNA binding protein, is a DNA and RNA-binding protein which regulates transcription and splicing. TARDBP is also involved in the regulation of CFTR splicing and promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TARD-BP may also be involved in microRNA biogenesis, apoptosis and cell division. TARDBP can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.

Long Name

TAR DNA-binding Protein 43

Alternate Names

ALS10, TARDBP, TDP43

Entrez Gene IDs

23435 (Human)

Gene Symbol

TARDBP

UniProt

NP_031401.1

Additional TDP-43/TARDBP Products

Product Documents for Human TDP-43/TARDBP (NP_031401.1) VersaClone cDNA

Product Datasheets

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Product Specific Notices for Human TDP-43/TARDBP (NP_031401.1) VersaClone cDNA

For research use only

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