Human STAT5b (NP_036580) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1451
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: STAT5b
Signal transduction and activator of transcription 5 (STAT5) is a member of the Jak/STAT signal transduction pathway and is activated by a variety of cytokines (IL22, IL6, IFN-α). STAT5 has two isoforms (A and B) that share 93% amino acid identity and bind the DNA consensus site TTCN3GAA. STAT5 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, translocates to the nucleus and activates transcription of specific genes. STAT5 is involved in a wide array of biological processes ranging from regulating apoptosis to adult mammary gland proliferation, differentiation and survival.
Long Name
Signal Transducer and Activator of Transcription 5b
Alternate Names
signal transducer and activator of transcription 5B, STAT5, transcription factor STAT5B
Gene Symbol
STAT5B
UniProt
Additional STAT5b Products
Product Documents for Human STAT5b (NP_036580) VersaClone cDNA
Product Specific Notices for Human STAT5b (NP_036580) VersaClone cDNA
For research use only
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