Human SOCS-3 (NP_003946.3) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3553
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: SOCS-3
SOCS (suppressor of cytokine signaling) proteins, also called CIS (cytokine-inducible SH2-domain containing) proteins, are a family of eight adaptor molecules active in signaling pathways that regulate innate and adaptive immune responses. All SOCS contain a single SH2 domain and a SOCS box, which recruits E3 ubiquitin ligase complexes, thus enhancing destruction of the molecules bound by SOCS proteins. SOCS proteins influence macrophage and dendritic cell activation and are essential for T cell development and differentiation.
Long Name
Suppressor Of Cytokine Signaling 3
Alternate Names
ATOD4, CIS3, Cish3, SOCS3, SSI-3
Gene Symbol
SOCS3
UniProt
Additional SOCS-3 Products
Product Documents for Human SOCS-3 (NP_003946.3) VersaClone cDNA
Product Specific Notices for Human SOCS-3 (NP_003946.3) VersaClone cDNA
For research use only
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