Human RECK (NP_066934) VersaClone cDNA

Known as reversion-inducing cysteine-rich protein with Kazal motifs, RECK is a GPI-anchored glycoprotein expressed in many tissues. RECK expression is suppressed in many tumors and cells transformed by various oncogenes. In normal cells, RECK downregulates MMP-9, a key enzyme involved in tumor invasion and metastasis.