Human Peripherin 2/PRPH2 (AAH74720) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC1019

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Key Product Details

Species

Human

Accession Number

AAH74720

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Peripherin 2/PRPH2

The protein encoded by the PRPH2 gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. (provided by RefSeq)

Long Name

Tetraspanin 32

Alternate Names

AOFMD, AVMD, CACD2, PRPH2, RDS, RP7, Tetraspanin-22, TSPAN22

Entrez Gene IDs

5961 (Human); 19133 (Mouse); 25534 (Rat)

Gene Symbol

PRPH2

UniProt

AAH74720

Additional Peripherin 2/PRPH2 Products

Product Documents for Human Peripherin 2/PRPH2 (AAH74720) VersaClone cDNA

Product Datasheets

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Product Specific Notices for Human Peripherin 2/PRPH2 (AAH74720) VersaClone cDNA

For research use only

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