Human PCSK9 (NP_777596) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC2709
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Proprotein Convertase 9/PCSK9
PCSK9 (Proprotein Convertase 9, is a serine endoprotease that is highly expressed in the liver, intestine, and kidney. PCSK9 promotes the degradation of low density lipoprotein receptor (LDLR) by inducing receptor degradation in the lysosome following its internalization. PCSK9 regulates the amounts of LDLR in the circulation and hence, modulates cholesterol levels. Nonsense or loss-of-function mutations in PCSK9 are associated with decreased plasma LDL cholesterol levels.
Alternate Names
FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9, PCSK9
Gene Symbol
PCSK9
UniProt
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Product Documents for Human PCSK9 (NP_777596) VersaClone cDNA
Product Specific Notices for Human PCSK9 (NP_777596) VersaClone cDNA
For research use only
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