Human MDGA1 (NP_705691) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1804
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: MDGA1
MDGA-1 (MAM domain-containing GPI anchor protein 1) is a 135-140 kDa, novel member of the Ig-superfamily. It is expressed on embryonic neurons destined for cortical layers 2/3, as well as migrating basilar pontine neurons and D1 interneurons of the spinal cord. Human proMDGA-1 is 937 amino acids (aa) in length (SwissProt #:Q8NFP4). It is a GPI-linked glycoprotein that contains six consecutive Ig-like domains (aa #24-631), followed by one fibronectin type III domain (aa #640-739), a MAM region (aa #751-918), and a cleavable propeptide (aa #933-955). There are at least three potential variants. One shows a 48 aa substitution for aa #936-955, a second shows a 58 aa substitution for aa #847-955, and a third shows a 51 aa substitution for aa #537-955. Over aa #19-931, human MDGA-1 is 95% aa identical to mouse MDGA-1.
Long Name
MAM Domain Containing Glycosylphosphatidylinositol Anchor 1
Alternate Names
GPIM, MAMDC3
Gene Symbol
MDGA1
UniProt
Additional MDGA1 Products
Product Documents for Human MDGA1 (NP_705691) VersaClone cDNA
Product Specific Notices for Human MDGA1 (NP_705691) VersaClone cDNA
For research use only
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