Human IRAK3 (NP_009130.2) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3757
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IRAK3
IL-1 receptor-associated kinases (IRAKs) are serine/threonine kinases that help mediate signaling from Toll-like receptor (TLR) and IL-1 receptor family members. Four human IRAKs have been identified: IRAK1, IRAK2, IRAK-M, and IRAK4. All IRAKs are multidomain proteins, containing a conserved N-terminal death domain as well as a central kinase domain that is only active in IRAK1 and IRAK4. IRAK4 mutations have been described in patients with recurrent bacterial infections and poor inflammatory responses.
Long Name
Interleukin-1 Receptor-Associated Kinase 3
Alternate Names
ASRT5, IRAK-M
Gene Symbol
IRAK3
UniProt
Additional IRAK3 Products
Product Documents for Human IRAK3 (NP_009130.2) VersaClone cDNA
Product Specific Notices for Human IRAK3 (NP_009130.2) VersaClone cDNA
For research use only
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