Human Integrin alpha 2b/CD41 (NP_000410) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC0402
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Integrin alpha 2b/CD41
Integrin alpha 2b (ITGA2b), also known as CD41 and GPIIb, is a transmembrane glycoprotein that is expressed by megakaryocytes and platelets. It is cleaved into two disulfide-linked chains (114 kDa and 22 kDa) during transit through the Golgi. Integrin alpha 2b associates with Integrin beta 3 to form complexes that interact with Fibrinogen, von Willebrand factor, Fibronectin, and Vitronectin. Integrin alpha 2b is required for platelet aggregation, and defects lead to disorders of coagulation.
Alternate Names
CD41, GP2B, GPIIb, GTA, HPA3, ITGA2b
Gene Symbol
ITGA2B
UniProt
Additional Integrin alpha 2b/CD41 Products
Product Documents for Human Integrin alpha 2b/CD41 (NP_000410) VersaClone cDNA
Product Specific Notices for Human Integrin alpha 2b/CD41 (NP_000410) VersaClone cDNA
For research use only
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