Human IL-29/IFN-lambda 1 (NP_742152.1) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3612
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: IL-29/IFN-lambda 1
Human/mouse IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3), and human IL-29 (IFN-lambda 1) are class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11 - 13% amino acid (aa) sequence identity) and type I IFN family (15 - 19% aa sequence identity). These cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and up-regulation of MHC class I antigen expression. The proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor beta (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Mouse IL-28 shares 61%, 62%, and 52% aa identity with human IL-28A, IL-28B, and IL-29, respectively.
Long Name
Interleukin 29
Alternate Names
IFN-lambda 1, IL29
Entrez Gene IDs
282618 (Human)
Gene Symbol
IFNL1
UniProt
Additional IL-29/IFN-lambda 1 Products
Product Documents for Human IL-29/IFN-lambda 1 (NP_742152.1) VersaClone cDNA
Product Specific Notices for Human IL-29/IFN-lambda 1 (NP_742152.1) VersaClone cDNA
For research use only
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