Human IFIH1/MDA5 (NP_071451.2) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC3648

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Key Product Details

Species

Human

Accession Number

NP_071451.2

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: IFIH1/MDA5

Gene ID: 64135 DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation.

Long Name

Melanoma Differentiation-Associated Protein 5

Alternate Names

AGS7, Helicard, Hlcd, IDDM19, IFIH1, IMD95, MDA-5, RH116, SGMRT1

Entrez Gene IDs

64135 (Human)

Gene Symbol

IFIH1

UniProt

NP_071451.2 (Human)

Additional IFIH1/MDA5 Products

Product Documents for Human IFIH1/MDA5 (NP_071451.2) VersaClone cDNA

Product Datasheets

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Product Specific Notices for Human IFIH1/MDA5 (NP_071451.2) VersaClone cDNA

For research use only

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