Human Histone Deacetylase 3/HDAC3(NP_003874) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC2872

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Key Product Details

Species

Human

Accession Number

NP_003874

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Histone Deacetylase 3/HDAC3

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone cetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone acetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Long Name

Histone Deacetylase 3

Alternate Names

HDAC3, KDAC3, RPD3-2, SMAP45

Entrez Gene IDs

8841 (Human); 15183 (Mouse)

Gene Symbol

HDAC3

UniProt

NP_003874

Additional Histone Deacetylase 3/HDAC3 Products

Product Documents for Human Histone Deacetylase 3/HDAC3(NP_003874) VersaClone cDNA

Product Datasheets

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Product Specific Notices for Human Histone Deacetylase 3/HDAC3(NP_003874) VersaClone cDNA

For research use only

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