Human HIF-3 alpha/HIF3A (NP_690008.2) VersaClone cDNA

R&D Systems, part of Bio-Techne | Catalog # RDC3435

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Key Product Details

Species

Human

Accession Number

NP_690008.2

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: HIF-3 alpha/HIF3A

Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia, by transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits, HIF1 alpha, HIF2 alpha, or HIF3 alpha. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis.

Long Name

Hypoxia Inducible Factor 3 Subunit Alpha

Alternate Names

BHLHe17, HIF3A, IPAS, MOP7, PASD7

Entrez Gene IDs

64344 (Human)

Gene Symbol

HIF3A

UniProt

NP_690008.2

Additional HIF-3 alpha/HIF3A Products

Product Documents for Human HIF-3 alpha/HIF3A (NP_690008.2) VersaClone cDNA

Product Datasheets

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Product Specific Notices for Human HIF-3 alpha/HIF3A (NP_690008.2) VersaClone cDNA

For research use only

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