Human Contactin-6 (NP_055276) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC1837
Key Product Details
Species
Human
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Contactin-6
Contactin-6, also known as NB-3, is a GPI-linked protein that is differentially expressed within various structures of the brain. In the cerebellum, it is presynaptically localized at synapses between excitatory glutamatergic parallel fibers and Purkinje cells. Contactin-6 knockout mice exhibit poor motor coordination. Contactin-6 associates in cis with CHL-1 and in trans with Notch-1 on oligodendrocytes. Its binding to Notch-1 triggers translocation of the Notch intracellular domain to the nucleus and promotes oligodendrogenesis.
Alternate Names
CNTN6, Contactin6, NB3
Gene Symbol
CNTN6
UniProt
Additional Contactin-6 Products
Product Documents for Human Contactin-6 (NP_055276) VersaClone cDNA
Product Specific Notices for Human Contactin-6 (NP_055276) VersaClone cDNA
For research use only
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