Cynomolgus Monkey GM-CSF R alpha (Unique) VersaClone cDNA
R&D Systems, part of Bio-Techne | Catalog # RDC3019
Key Product Details
Species
Cynomolgus Monkey
Accession Number
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: GM-CSF R alpha
The high affinity receptor for granulocyte-macrophage colony stimulating factor (GM-CSF) consists of two subunits; an 80 kDa cytokine-specific alpha-subunit (CD116), and a 120 kDa non-specific, signal transducing beta-subunit (CD131). Analogous with other cytokine signaling mechanisms, CD131 is also shared with the cytokine specific alpha-subunits of the IL-3 and IL-5 receptors. In the absence of CD131, the CD116 alpha-subunit binds GM-CSF with low affinity. GM-CSF receptors are highly expressed on neutrophils, monocytes, oligodendrocytes, megakaryocytes, eosinophils, and myeloid leukemia cells.
Long Name
Granulocyte Macrophage Growth Factor Receptor alpha
Alternate Names
CD116, CSF2R, CSF2RA, CSF2RY, GM-CSFRa, GMCSFR alpha
Gene Symbol
CSF2RA
UniProt
Additional GM-CSF R alpha Products
Product Documents for Cynomolgus Monkey GM-CSF R alpha (Unique) VersaClone cDNA
Product Specific Notices for Cynomolgus Monkey GM-CSF R alpha (Unique) VersaClone cDNA
For research use only
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