DNA polymerase eta is specifically involved in DNA repair. It plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. It also plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. It targets POLI to replication foci (referenced from swissprot).

Long Name

Xeroderma Pigmentosum Variant Type Protein

Alternate Names

DNA Polymerase, eta, POLH, RAD30A

Gene Symbol

POLH

Additional XPV Products

Product Documents for XPV/DNA polymerase eta Antibody [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for XPV/DNA polymerase eta Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

XPV/DNA polymerase eta Antibody [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # AF3417B

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all XPV Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Applications for XPV/DNA polymerase eta Antibody [Biotin]

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: XPV