Viral CMV UL146/vCXC1 Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF620
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Viral
Cited:
Human
Applications
Validated:
Western Blot
Cited:
ELISA Detection
Label
Biotin
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
E. coli-derived recombinant viral CMV UL146/vCXC1
Specificity
Detects viral CMV UL146/vCXC1 in direct ELISAs and Western blots.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Viral CMV UL146/vCXC1 Biotinylated Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Viral CMV UL146/vCXC1 (Catalog # 620-CM)
Sample: Recombinant Viral CMV UL146/vCXC1 (Catalog # 620-CM)
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: UL146/vCXC1
Cytomegalovirus (CMV), a member of the beta herpesvirus subfamily, typically causes subclinical or latent infections in the normal adult population. However, CMV can cause congenital disease during pregnancy and is a human opportunistic pathogen that affects immunocompromised individuals. The CMV genome has been shown to contain homologs of cellular immunomodulatory proteins, including US28 (a CC chemokine receptor) and a MHC class I homolog. Virulent CMV clinical isolates have also been shown to carry at least 19 genes, designated UL133-UL151, that are not found in laboratory strains that have lost virulence characteristics. Two of these genes, UL146 and UL147, exhibit sequence similarity to CXC chemokines.
The CMV UL146 open-reading frame encodes a 117 amino acid residue precursor protein with a predicted 22 residues signal peptide that is cleaved to generate the mature protein. Recombinant UL146 has been shown to induce calcium mobilization, chemotaxis and degranulation of neutrophils.
Long Name
Cytomegalovirus UL146
Alternate Names
HHV5wtgp117, vCXC1, vCXCL1, Y18
Additional UL146/vCXC1 Products
Product Documents for Viral CMV UL146/vCXC1 Biotinylated Antibody
Product Specific Notices for Viral CMV UL146/vCXC1 Biotinylated Antibody
For research use only
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