Vanilloid R1/TRPV1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB120-3487

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NB120-3487
NB120-3487-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot, Immunocytochemistry/ Immunofluorescence

Cited:

Western Blot, Immunocytochemistry/ Immunofluorescence, IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all Vanilloid R1/TRPV1 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues T(7) D L G A A A D P L Q K D T C(21) of human VR1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Vanilloid R1/TRPV1 Antibody

Immunohistochemistry-Frozen: Vanilloid R1/TRPV1 Antibody [NB120-3487]

Immunohistochemistry-Frozen: Vanilloid R1/TRPV1 Antibody [NB120-3487]

Immunohistochemistry-Frozen: Vanilloid R1/TRPV1 Antibody [NB120-3487] - Frozen human skin tissue sections were fixed with paraformaldehyde and stained. Vanilloid Receptor 1 staining is shown in red. Data courtesy of the Innovators Program.
Immunohistochemistry-Frozen: Vanilloid R1/TRPV1 Antibody [NB120-3487]

Immunohistochemistry-Frozen: Vanilloid R1/TRPV1 Antibody [NB120-3487]

Immunohistochemistry-Frozen: Vanilloid R1/TRPV1 Antibody [NB120-3487] - Immunolocalization of VR1 in human glabrous skin.

Applications for Vanilloid R1/TRPV1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Frozen

1 ug/ml

Western Blot

1:100 - 1:2000
Application Notes
Use in ICC/IF reported in scientific literature (PMID:33362470). WB usage was reported in scientific literature. IF: Staining of VR1 in human prostatic urethra results in fibrous staining within the epithelial cells.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Vanilloid R1/TRPV1

Vanilloid Receptor 1 (VR1), also known as capsaicin receptor, responds to both capsaicin, the pungent ingredient in hot peppers, and thermal stimuli within the noxious temperature range. This receptor is structurally related to the TRP family of ion channels and is predicted to contain 6 trans-membrane domains, a P-loop membrane domain and 3 ankyrin repeat domains. VR1 is highly permeable to divalent cations, including calcium and magnesium, as well as the monovalent cations sodium and potassium. Expression of VR1 appears to be limited to neurons within the sensory ganglia.

Long Name

Vanilloid Receptor 1/Transient Receptor Potential Cation Channel 1

Alternate Names

Capsaicin Receptor, TRPV1, VanilloidR1, VR1

Entrez Gene IDs

7442 (Human)

Gene Symbol

TRPV1

UniProt

Q52PU4 (Human)

Additional Vanilloid R1/TRPV1 Products

Product Documents for Vanilloid R1/TRPV1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Vanilloid R1/TRPV1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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