ULK1 [p Ser467] Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16957

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NBP3-16957-100ul
NBP3-16957-20ul
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ULK1 Antibodies »

Product Specifications

Immunogen

A synthetic phosphorylated peptide around S467 of human ULK1 (NP_003556.2). SGSTS

Modification

p Ser 467

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ULK1 [p Ser467] Antibody

Western Blot: ULK1 [p Ser467] AntibodyAzide and BSA Free [NBP3-16957]

Western Blot: ULK1 [p Ser467] AntibodyAzide and BSA Free [NBP3-16957]

Western Blot: ULK1 [p Ser467] Antibody [NBP3-16957] - Western blot analysis of extracts of various cell lines, using ULK1 antibody (NBP3-16957) at 1:1000 dilution.HeLa and Jurkat cells were treated by Serum-starvation overnight at 37C. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.

Applications for ULK1 [p Ser467] Antibody

Application
Recommended Usage

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ULK1

ULK1 belongs to the serine/threonine protein kinase family. It is involved in axon growth and plays an essential role in neurite branching during sensory axon outgrowth. Knockdown of ULK1 results in impaired endocytosis of nerve growth factor (NGF), excessive axon arborization, and severely stunted axon elongation indicating that ULK1 mediates a non clathrin coated endocytosis in sensory growth cones. Knockdown of ULK1 also inhibits the autophagic response. It appears to act as a convergence point for multiple signals that regulate autophagy, and in turn interacts with a large number of autophagy related (Atg) proteins.

Long Name

Serine/threonine-protein kinase ULK1

Alternate Names

ATG1, hATG1, KIAA0722

Gene Symbol

ULK1

Additional ULK1 Products

Product Documents for ULK1 [p Ser467] Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ULK1 [p Ser467] Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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