UCP3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58840

Novus Biologicals, part of Bio-Techne
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NBP2-58840
NBP2-58840-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all UCP3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: AEVVTYDILKEKLLDYHLLTDNFPCHFV

Reactivity Notes

Mouse 82%, Rat 86%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for UCP3 Antibody - BSA Free

Immunohistochemistry-Paraffin: UCP3 Antibody [NBP2-58840]

Immunohistochemistry-Paraffin: UCP3 Antibody [NBP2-58840]

Immunohistochemistry-Paraffin: UCP3 Antibody [NBP2-58840] - Staining of human skin shows low expression as expected.
Immunohistochemistry-Paraffin: UCP3 Antibody [NBP2-58840]

Immunohistochemistry-Paraffin: UCP3 Antibody [NBP2-58840]

Immunohistochemistry-Paraffin: UCP3 Antibody [NBP2-58840] - Staining of human skeletal muscle shows high expression.
Immunohistochemistry-Paraffin: UCP3 Antibody [NBP2-58840]

Immunohistochemistry-Paraffin: UCP3 Antibody [NBP2-58840]

Immunohistochemistry-Paraffin: UCP3 Antibody [NBP2-58840] - Staining in human skeletal muscle and skin tissues using anti-UCP3 antibody. Corresponding UCP3 RNA-seq data are presented for the same tissues.

Applications for UCP3 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: UCP3

The uncoupling proteins (UCPs) are found in the inner mitochondrial membranes and belong to a family of mitochondrial anion transport proteins that include the phosphate and oxologutarate carriers and the ADP/ATP translocator. Three UCP subtypes have been identified and cloned. UCP 1 is abundantly expressed in brown adipose tissue of mammals. UCP 1 allows proton re-entry into the mitochondrial matrix without involving the F0-F1 ATPase which produces heat instead of ATP. It is thought that UCP 2 and 3 also dissipate the mitochondrial proton gradient produced by the respiratory chain in cells and tissues within which they are expressed. Studies have shown UCP 2 to be expressed by a variety of tissues. UCP 3 is expressed predominantly in brown adipose tissue, skeletal muscle, at lower levels in heart and smooth muscle, and is absent in liver and kidney.

Long Name

Uncoupling Protein 3 (Mitochondrial, Proton Carrier)

Alternate Names

SLC25A9

Gene Symbol

UCP3

Additional UCP3 Products

Product Documents for UCP3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for UCP3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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