TRPV6 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-45715

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NBP3-45715
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRPV6 Antibodies »

Product Specifications

Immunogen

transient receptor potential cation channel, subfamily V, member 6. (Uniprot# Q9H1D0)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TRPV6 Antibody - BSA Free

TRPV6 Antibody - BSA Free

Western Blot: TRPV6 Antibody - BSA Free [NBP3-45715] -

Western Blot: TRPV6 Antibody - BSA Free [NBP3-45715] - Human placenta tissue were subjected to SDS PAGE followed by western blot with (TRPV6 Antibody) at dilution of 1:1000
TRPV6 Antibody - BSA Free

Immunoprecipitation: TRPV6 Antibody - BSA Free [NBP3-45715] -

Immunoprecipitation: TRPV6 Antibody - BSA Free [NBP3-45715] - IP Result of anti-TRPV6 (IP:, 4ug; Detection: 1:300) with mouse kidney tissue lysate 4000ug.

Applications for TRPV6 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:100

Immunoprecipitation

1:200-1:1000

Western Blot

1:500-1:5000
Application Notes
Theoretical Molecular Weight is 82 kDa, 70 kDa

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: TRPV6

Calcium-permeable channels, such as TRPV6, participate in neurotransmission, muscle contraction, and exocytosis by providing calcium as an intracellular second messenger. Depending on the tissue, transcellular calcium transport may be regulated by vitamin D, parathyroid hormone (PTH), or calcitonin (CALCA); FUNCTION: Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating. SUBUNIT: Homotetramer and probably heterotetramer with TRPV5. Interacts with TRPV5. Interacts with S100A10 and probably with the ANAX2-S100A10 heterotetramer. The interaction with S100A10 is required for the trafficking to the plasma membrane. Interacts with BSPRY. Interacts with calmodulin. SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.

Long Name

Transient Receptor Potential Cation Channel Subfamily V Member 6

Alternate Names

ABP/ZF, CaT-L, CaT1, ECAC2, ZFAB

Gene Symbol

TRPV6

Additional TRPV6 Products

Product Documents for TRPV6 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TRPV6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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