Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry, Immunoprecipitation

Label

Biotin

Antibody Source

Monoclonal Mouse IgG1 Clone # 672722

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TRIM21 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human TRIM21
Arg195-Pro293
Accession # P19474

Specificity

Detects human TRIM21 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) TRIM, rhTRIM5, rhTRIM5a, rhTRIM32, rhTRIF (aa 29-204), or rhTRIF (aa 474-618) is observed

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for TRIM21/SSA1 Antibody (672722) [Biotin]

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TRIM21

SSA1 encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Long Name

Tripartite Motif-containing Protein 21

Alternate Names

RNF81, Ro52, SSA1

Gene Symbol

TRIM21

Additional TRIM21 Products

Product Documents for TRIM21/SSA1 Antibody (672722) [Biotin]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TRIM21/SSA1 Antibody (672722) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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