TMEM38A Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76247

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NBP1-76247
NBP1-76247-0.025mg
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Conjugate
Catalog #
Alexa Fluor 350
NBP1-76247AF350
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Alexa Fluor 405
NBP1-76247AF405
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Alexa Fluor 488
NBP1-76247AF488
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Alexa Fluor 532
NBP1-76247AF532
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Alexa Fluor 594
NBP1-76247AF594
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Alexa Fluor 647
NBP1-76247AF647
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Alexa Fluor 700
NBP1-76247AF700
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Alexa Fluor 750
NBP1-76247AF750
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Alexa Fluor Plus 405
NBP1-76247AFP405
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Alexa Fluor Plus 488
NBP1-76247AFP488
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Alexa Fluor Plus 555
NBP1-76247AFP555
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Alexa Fluor Plus 594
NBP1-76247AFP594
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Alexa Fluor Plus 647
NBP1-76247AFP647
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Alexa Fluor Plus 680
NBP1-76247AFP680
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Allophycocyanin
NBP1-76247APC
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Biotin
NBP1-76247B
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CoraFluor 1
NBP1-76247CL1
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DyLight 350
NBP1-76247UV
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DyLight 405
NBP1-76247V
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DyLight 488
NBP1-76247G
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DyLight 550
NBP1-76247R
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DyLight 594
NBP1-76247DL594
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DyLight 650
NBP1-76247C
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DyLight 680
NBP1-76247FR
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DyLight 755
NBP1-76247IR
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FITC
NBP1-76247F
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HRP
NBP1-76247H
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Janelia Fluor 525
NBP1-76247JF525
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Janelia Fluor 549
NBP1-76247JF549
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Janelia Fluor 646
NBP1-76247JF646
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Janelia Fluor 669
NBP1-76247JF669
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mFluor Violet 450 SE
NBP1-76247MFV450
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mFluor Violet 500 SE
NBP1-76247MFV500
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mFluor Violet 610 SE
NBP1-76247MFV610
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PE
NBP1-76247PE
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PerCP
NBP1-76247PCP
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (94%), Rabbit (94%). Backed by our 100% Guarantee.

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all TMEM38A Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human TMEM38A. The immunogen is located within the last 50 amino acids of TMEM38A.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TMEM38A Antibody - BSA Free

Western Blot: TMEM38A AntibodyBSA Free [NBP1-76247]

Western Blot: TMEM38A AntibodyBSA Free [NBP1-76247]

Western Blot: TMEM38A Antibody [NBP1-76247] - Rat skeletal muscle tissue lysate with TMEM38A antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
TMEM38A Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: TMEM38A Antibody - BSA Free [NBP1-76247] -

Immunocytochemistry/ Immunofluorescence: TMEM38A Antibody - BSA Free [NBP1-76247] - Immunofluorescence of TMEM38A in mouse skeletal muscle tissue with TMEM38A antibody at 20 u/mL.

Applications for TMEM38A Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TMEM38A

TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure; the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.

Alternate Names

transmembrane protein 38ATRIC-AMGC3169, TRICA, trimeric intracellular cation channel type A

Gene Symbol

TMEM38A

UniProt

AAH01195 (Human)

Additional TMEM38A Products

Product Documents for TMEM38A Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for TMEM38A Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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