TMEM119 Antibody - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-30792
Key Product Details
Validated by
Orthogonal Validation, Independent Antibodies
Species Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
BSA Free
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: GDGARMVEGRGAEEEEKGSQEGDQEVQGHGVPVETPEAQEEPCSGVLEGAVVAGEGQGELEGSLLLAQEAQGPVGPPESPCACSSVHPS
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for TMEM119 Antibody - BSA Free
Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30792]
Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30792] - Staining of human cerebral cortex, liver, lymph node and testis using Anti-TMEM119 antibody NBP2-30792 (A) shows similar protein distribution across tissues to independent antibody NBP2-30551 (B).Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30792]
Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30792] - Staining of human lymph node strong positivity in reticular fibers in germinal center cells.Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30792]
Immunohistochemistry-Paraffin: TMEM119 Antibody [NBP2-30792] - Staining of human cerebral cortex shows moderate to strong membranous positivity in microglia.Applications for TMEM119 Antibody - BSA Free
Application
Recommended Usage
Immunohistochemistry
1:500 - 1:1000
Immunohistochemistry-Paraffin
1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: TMEM119
ATF4 is an approximately 38 kDa member of the bzip family of transcription factors. It plays an important role autophagy, the unfolded protein response, and the response to oxygen and nutrient deprivation. These functions are regulated by the dimerization of ATF4 with the leucine zipper protein FIAT. ATF4 contains a basic DNA-binding domain (aa 280-300) and a leucine zipper domain (aa 306-334).
Additional TMEM119 Products
Product Documents for TMEM119 Antibody - BSA Free
Product Specific Notices for TMEM119 Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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