Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Janelia Fluor 549

Antibody Source

Monoclonal Rat IgG2A Clone # 285923

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all TLR1 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse TLR1
Ser25-Asp581
Accession # Q9EPQ1

Specificity

Detects mouse TLR1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) IL-1 RI, II, 3, 6, 9, recombinant human IL-1 R8, rmIL-18 R, rmIL-18 Rb, rmMD-1, rmRP105, rmSIGIRR, rmTLR2, 3, 4, or 6 is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for TLR1 Antibody (285923) [Janelia Fluor® 549]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TLR1

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells where they form heterodimers that can recognize triacylated lipoproteins.

Long Name

Toll-like Receptor 1

Alternate Names

CD281

Gene Symbol

TLR1

Additional TLR1 Products

Product Documents for TLR1 Antibody (285923) [Janelia Fluor® 549]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for TLR1 Antibody (285923) [Janelia Fluor® 549]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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