TLR (Intracellular) Screening Antibody Pack

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-25085

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-25085
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species

Human, Mouse

Applications

Dot Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Product Specifications

Application Notes

See individual datasheets of components for their validated applications

Reactivity Notes

See individual datasheets of components for their validated species

Scientific Data Images for TLR (Intracellular) Screening Antibody Pack

Immunohistochemistry: TLR (Intracellular) Screening Antibody Pack [NBP2-25085]

Immunohistochemistry: TLR (Intracellular) Screening Antibody Pack [NBP2-25085]

Immunohistochemistry: TLR (Intracellular) Screening Antibody Pack [NBP2-25085] - The expression of TLR-7 in the hippocampal brain region. The immunofluorescence of TLR7 recognized by Alexa 488, green. GFAP recognized by Alexa 594, red. NEUN recognized by Alexa 633, (blue) and merged image in the hippocampal region. NeuN and GFAP were applied to show the distribution of TLR7 within neuronal and supportive tissue populations. Scale bar 80 um. Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0222818) licensed under a CC-BY license. TLR7 Antibody [NBP2-24906]
Flow Cytometry: TLR (Intracellular) Screening Antibody Pack [NBP2-25085]

Flow Cytometry: TLR (Intracellular) Screening Antibody Pack [NBP2-25085]

Flow Cytometry: TLR (Intracellular) Screening Antibody Pack [NBP2-25085] - Expression of TLR3 and TLR8 in Fravel, L363, OPM1, RPMI8226, XG1, and NCI-H929 as determined by flow cytometry. HCMLs were stained using an intracellular staining protocol with TLR3 and TLR8 antibodies followed by relevant secondary fluorescent-conjugated antibodies. Filled histograms (purple) represent the isotype controls and the open histograms (red) indicate TLR8. Data are representative for analysis of >= 2 independent experiments. Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0060671) licensed under a CC-BY license. TLR3 Antibody (40C1285.6) [NBP2-24875] and TLR8 Antibody (44C143) [NBP2-24917]
Knockdown Validated: TLR (Intracellular) Screening Antibody Pack [NBP2-25085]

Western Blot: TLR (Intracellular) Screening Antibody Pack [NBP2-25085]

Western Blot: TLR (Intracellular) Screening Antibody Pack [NBP2-25085] - Expression of TLR-9 protein in HB cells before and after 48 hr of transfection. Beta-actin was used as an internal control. Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0092748) licensed under a CC-BY license. TLR9 Antibody (26C593.2) [NBP2-24729]
View 3 more images

Formulation, Preparation, and Storage

Concentration

Concentration of individual antibodies may be found on the vial label. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TLR (Intracellular) Screening

The Toll-like receptor (TLR) family in mammals comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLR3, 7, 8, and 9 are expressed in the intracellular organelles. TLR7 and TLR8 have a common ligand, viral single-stranded RNA. TLR3 is activated by viral double-stranded RNA. TLR9 responds to bacterial unmethylated CpG DNA. Ten human homologs of TLRs (TLR1-10) have been described

Additional TLR (Intracellular) Screening Products

Product Documents for TLR (Intracellular) Screening Antibody Pack

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for TLR (Intracellular) Screening Antibody Pack

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Packs are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.