Thioredoxin-1 Antibody - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31090
Key Product Details
Species Reactivity
Validated:
Human, Mouse
Predicted:
Rhesus Macaque (100%). Backed by our 100% Guarantee.
Applications
Western Blot, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
BSA Free
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Thioredoxin-1. The exact sequence is proprietary.
Localization
Cytoplasm
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
12 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Description
Novus Biologicals Rabbit Thioredoxin-1 Antibody - BSA Free (NBP1-31090) is a polyclonal antibody validated for use in WB, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
Scientific Data Images for Thioredoxin-1 Antibody - BSA Free
![Western Blot: Thioredoxin-1 Antibody [NBP1-31090]](https://resources.bio-techne.com/images/products/Thioredoxin-Antibody-Western-Blot-NBP1-31090-img0001.jpg "Western Blot: Thioredoxin-1 Antibody [NBP1-31090]")
Western Blot: Thioredoxin-1 Antibody [NBP1-31090]
Western Blot: Thioredoxin Antibody [NBP1-31090] - A: H1299 B: HeLa S3 12% SDS PAGE diluted at 1:3000![Immunocytochemistry/ Immunofluorescence: Thioredoxin-1 Antibody [NBP1-31090]](https://resources.bio-techne.com/images/products/Thioredoxin-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-31090-img0004.jpg "Immunocytochemistry/ Immunofluorescence: Thioredoxin-1 Antibody [NBP1-31090]")
Immunocytochemistry/ Immunofluorescence: Thioredoxin-1 Antibody [NBP1-31090]
Immunocytochemistry/Immunofluorescence: Thioredoxin Antibody [NBP1-31090] - HeLa cells were fixed in ice-cold MeOH for 5 min. Green: Trx protein stained by Trx antibody [N3C3] diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um.Applications for Thioredoxin-1 Antibody - BSA Free
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
1:100-1:1000
Western Blot
1:500-1:3000
Application Notes
IP-Assay dependent
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
0.1M Tris, 0.1M Glycine, 10% Glycerol
Format
BSA Free
Preservative
0.01% Thimerosal
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Thioredoxin-1
Thioredoxins (Trxs) are a group of small ubiquitous proteins that are key regulators of cellular redox balance. The mammalian Trx family includes the secreted and cellular protein (Trx-1), the mitochondria-specific Trx-2, the Trx-like cytosolic protein p32TrxL, a truncated version of Trx-1 known as Trx80, and the thioredoxin-related protein, TRP-14. Trx-1 is secreted by lymphocytes, hepatocytes, fibroblasts, and several tumor cells. Trx-1 acts as a growth factor an, antioxidant, a cofactor that provides reducing equivalents, and a transcriptional regulator. Expression of Trx-1 is increased under various stress conditions such as hypoxia and viral and bacterial infections. It also serves as a biomarker for rheumatoid arthritis.
Alternate Names
Thioredoxin1, Trx1, TXN, TXN1
Gene Symbol
TXN
Additional Thioredoxin-1 Products
Product Documents for Thioredoxin-1 Antibody - BSA Free
Product Specific Notices for Thioredoxin-1 Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information go to www.P65Warnings.ca.gov.