Thioredoxin-1 Antibody (214) - Azide and BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89460
Recombinant Monoclonal Antibody
![Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460]](https://resources.bio-techne.com/images/products/Thioredoxin-1-Antibody-214-Immunohistochemistry-Paraffin-NBP2-89460-img0002.jpg "Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460]")
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # 214 expressed in HEK293
Format
Azide and BSA Free
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human Thioredoxin-1 (Uniprot#: P10599; Met1-Val105).
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Description
This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
Scientific Data Images for Thioredoxin-1 Antibody (214) - Azide and BSA Free
Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460]
Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460] - Staining of human TXN in human appendix with rabbit monoclonal antibody (1:200). Positive staining was localized to intestinal gland.![Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460]](https://resources.bio-techne.com/images/products/Thioredoxin-1-Antibody-214-Immunohistochemistry-Paraffin-NBP2-89460-img0001.jpg "Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460]")
Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460]
Immunohistochemistry-Paraffin: Thioredoxin-1 Antibody (214) [NBP2-89460] - Staining of human TXN in human colon with rabbit monoclonal antibody (1:200). Positive staining was localized to colonic gland.Applications for Thioredoxin-1 Antibody (214) - Azide and BSA Free
Application
Recommended Usage
Immunohistochemistry-Paraffin
1:100-1:500
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
0.2 um filtered solution in PBS
Format
Azide and BSA Free
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Thioredoxin-1
Thioredoxins (Trxs) are a group of small ubiquitous proteins that are key regulators of cellular redox balance. The mammalian Trx family includes the secreted and cellular protein (Trx-1), the mitochondria-specific Trx-2, the Trx-like cytosolic protein p32TrxL, a truncated version of Trx-1 known as Trx80, and the thioredoxin-related protein, TRP-14. Trx-1 is secreted by lymphocytes, hepatocytes, fibroblasts, and several tumor cells. Trx-1 acts as a growth factor an, antioxidant, a cofactor that provides reducing equivalents, and a transcriptional regulator. Expression of Trx-1 is increased under various stress conditions such as hypoxia and viral and bacterial infections. It also serves as a biomarker for rheumatoid arthritis.
Alternate Names
Thioredoxin1, Trx1, TXN, TXN1
Gene Symbol
TXN
Additional Thioredoxin-1 Products
Product Documents for Thioredoxin-1 Antibody (214) - Azide and BSA Free
Product Specific Notices for Thioredoxin-1 Antibody (214) - Azide and BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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