TGF-beta Antibody (TGFB/7240)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23695
![TGF-beta Antibody (TGFB/7240) Immunohistochemistry-Paraffin: TGF-beta Antibody (TGFB/7240) [NBP3-23695] -](https://resources.bio-techne.com/images/products/nbp3-23695_mouse-tgf-beta-mab-tgfb-7240-2412025863645.jpg "Immunohistochemistry-Paraffin: TGF-beta Antibody (TGFB/7240) [NBP3-23695] -")
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG Clone # TGFB/7240
Concentration
0.2 mg/ml
Product Specifications
Immunogen
Recombinant fragment (around aa200-390) of human TGF-beta protein
Localization
Cytoplasm. Extracellular (secreted).
Specificity
This monoclonal antibody recognizes TGF beta 1, 2 and 3.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG
Description
Store at 2 to 8C. Non-hazardous. No MSDS required.
Scientific Data Images for TGF-beta Antibody (TGFB/7240)
Immunohistochemistry-Paraffin: TGF-beta Antibody (TGFB/7240) [NBP3-23695] -
Immunohistochemistry-Paraffin: TGF-beta Antibody (TGFB/7240) [NBP3-23695] - Formalin-fixed, paraffin-embedded human placenta stained with TGF-beta Antibody (TGFB/7240). Inset: PBS instead of primary antibody; secondary only negative control.Applications for TGF-beta Antibody (TGFB/7240)
Application
Recommended Usage
Immunohistochemistry-Paraffin
1-2ug/ml
Application Notes
Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
10mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C.
Background: TGF-beta
TGF-beta 1 (Transforming Growth Factor beta 1) is a pleiotrophic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. TGF-beta 1 associates with LAP to form a latent complex. It can be is activated from latency by plasmin, matrix metalloproteases, thrombospondin 1, and a subset of integrins. TGF-beta 1 signals through complexes of TGF-beta RII with TGF-beta RI/ALK-5 or ALK-1. TGF-beta signaling is modulated by the accessory receptors TGF-beta RIII/Betaglycan and Endoglin/CD105.
Long Name
Transforming Growth Factor beta
Alternate Names
TGFbeta
Gene Symbol
TGFB1
Additional TGF-beta Products
Product Documents for TGF-beta Antibody (TGFB/7240)
Product Specific Notices for TGF-beta Antibody (TGFB/7240)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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