SYPL2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77362

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NBP1-77362
NBP1-77362-0.025mg
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Conjugate
Catalog #
Alexa Fluor 350
NBP1-77362AF350
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Alexa Fluor 405
NBP1-77362AF405
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Alexa Fluor 488
NBP1-77362AF488
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Alexa Fluor 532
NBP1-77362AF532
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Alexa Fluor 594
NBP1-77362AF594
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Alexa Fluor 647
NBP1-77362AF647
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Alexa Fluor 700
NBP1-77362AF700
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Alexa Fluor 750
NBP1-77362AF750
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Alexa Fluor Plus 405
NBP1-77362AFP405
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Alexa Fluor Plus 488
NBP1-77362AFP488
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Alexa Fluor Plus 555
NBP1-77362AFP555
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Alexa Fluor Plus 594
NBP1-77362AFP594
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Alexa Fluor Plus 647
NBP1-77362AFP647
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Alexa Fluor Plus 680
NBP1-77362AFP680
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Allophycocyanin
NBP1-77362APC
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Biotin
NBP1-77362B
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CoraFluor 1
NBP1-77362CL1
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DyLight 350
NBP1-77362UV
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DyLight 405
NBP1-77362V
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DyLight 488
NBP1-77362G
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DyLight 550
NBP1-77362R
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DyLight 594
NBP1-77362DL594
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DyLight 650
NBP1-77362C
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DyLight 680
NBP1-77362FR
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DyLight 755
NBP1-77362IR
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FITC
NBP1-77362F
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HRP
NBP1-77362H
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Janelia Fluor 525
NBP1-77362JF525
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Janelia Fluor 549
NBP1-77362JF549
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Janelia Fluor 646
NBP1-77362JF646
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Janelia Fluor 669
NBP1-77362JF669
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mFluor Violet 450 SE
NBP1-77362MFV450
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mFluor Violet 500 SE
NBP1-77362MFV500
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mFluor Violet 610 SE
NBP1-77362MFV610
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PE
NBP1-77362PE
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PerCP
NBP1-77362PCP
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Rabbit (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all SYPL2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human SYPL. The immunogen is located within the last 50 amino acids of SYPL2.

Specificity

At least two isoforms of SYPL2 are known to exist. SYPL2 antibody will not cross-react with SYPL1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SYPL2 Antibody - BSA Free

Western Blot: SYPL2 AntibodyBSA Free [NBP1-77362]

Western Blot: SYPL2 AntibodyBSA Free [NBP1-77362]

Western Blot: SYPL2 Antibody [NBP1-77362] - Human spleen tissue lysate with SYPL2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
SYPL2 Antibody - BSA Free

Immunohistochemistry: SYPL2 Antibody - BSA Free [NBP1-77362] -

Immunohistochemistry: SYPL2 Antibody - BSA Free [NBP1-77362] - Immunohistochemistry of SYPL2 in human spleen tissue with SYPL2 antibody at 2.5 ug/mL.
SYPL2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: SYPL2 Antibody - BSA Free [NBP1-77362] -

Immunocytochemistry/ Immunofluorescence: SYPL2 Antibody - BSA Free [NBP1-77362] - Immunofluorescence of SYPL2 in Human Spleen cells with SYPL2 antibody at 20 ug/mL.

Applications for SYPL2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SYPL2

SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family. SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle. SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function. Co-expression of SYPL2 and RyR in cultured cells leads to apoptotic cell death resulting from the depletion of Ca2+ from the intracellular stores. At least two isoforms of SYPL2 are known to exist. SYPL2 antibody will not cross-react with SYPL1.

Alternate Names

MG29, mitsugumin-29, synaptophysin-like 2, synaptophysin-like protein 2

Gene Symbol

SYPL2

UniProt

NP_001035799 (Human)

Additional SYPL2 Products

Product Documents for SYPL2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SYPL2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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