RXR beta/NR2B2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57755

Novus Biologicals, part of Bio-Techne
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NBP2-57755
NBP2-57755-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rat (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Chromatin Immunoprecipitation-exo-Seq

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all RXR beta/NR2B2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: VAGGEQQTPEPEPGEAGRDGMGDSGRDSRSP

Reactivity Notes

Mouse 87%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit RXR beta/NR2B2 Antibody - BSA Free (NBP2-57755) is a polyclonal antibody validated for use in ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for RXR beta/NR2B2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: RXR beta/NR2B2 Antibody [NBP2-57755]

Immunocytochemistry/ Immunofluorescence: RXR beta/NR2B2 Antibody [NBP2-57755]

Immunocytochemistry/Immunofluorescence: RXR beta/NR2B2 Antibody [NBP2-57755] - Staining of human cell line SK-MEL-30 shows localization to nucleus. Antibody staining is shown in green.
RXR beta/NR2B2 Antibody - BSA Free Chromatin Immunoprecipitation-exo-Seq: RXR beta/NR2B2 Antibody - BSA Free [NBP2-57755]

Chromatin Immunoprecipitation-exo-Seq: RXR beta/NR2B2 Antibody - BSA Free [NBP2-57755]

ChIP-Exo-Seq composite graph for Anti-RXRB (NBP2-57755) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.

Applications for RXR beta/NR2B2 Antibody - BSA Free

Application
Recommended Usage

Chromatin Immunoprecipitation-exo-Seq

1-10ug per reaction

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: RXR beta/NR2B2

Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).

Long Name

Retinoid X Receptor, beta

Alternate Names

H-2RIIBP, NR2B2, RXRB

Gene Symbol

RXRB

Additional RXR beta/NR2B2 Products

Product Documents for RXR beta/NR2B2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for RXR beta/NR2B2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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