PBP, also known as RKIP (RAF kinase inhibitor protein), binds ATP, opioids and phosphatidylethanolamine. PBP is able to regulate Aurora kinase B expression and the spindle checkpoint through interaction with the RAF1/MEK/ERK cascade. PBP is able to bind to RAF1 and MEK and competitively disrupt the interaction between these proteins. PBP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. It increases the production of choline acetyltransferase but not acetylcholinesterase. PBP has been implicated as a suppressor of metastasis.

Long Name

Raf kinase inhibitory protein

Alternate Names

HCNPpp, Neuropolypeptide h3, PBP, PEBP-1, PEBP1

Gene Symbol

PEBP1

Additional RKIP Products

Product Documents for RKIP/PBP Antibody [FITC]

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Product Specific Notices for RKIP/PBP Antibody [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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RKIP/PBP Antibody [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # AF4538F

Key Product Details

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Applications for RKIP/PBP Antibody [FITC]

Western Blot

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Background: RKIP