RGM-B Antibody (398528) [FITC]
Novus Biologicals, part of Bio-Techne | Catalog # FAB3630F
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
FITC (Excitation = 495 nm, Emission = 519 nm)
Antibody Source
Monoclonal Mouse IgG2B Clone # 398528
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human RGM-B isoform 1
Gly46-Ser411
Accession # Q6NW40
Gly46-Ser411
Accession # Q6NW40
Specificity
Detects human RGM-B in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse RGM-B, recombinant human (rh) RGM-A, or rhRGM-C is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for RGM-B Antibody (398528) [FITC]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: RGM-B
The repulsive guidance molecule (RGM) family of molecules contains three uniquely structured GPI-linked glycoproteins that participate in a variety of activities. Termed RGM-A, -B and -C, they are 40-45 kDa in size, show generally nonoverlapping fetal expression patterns, and serve as BMP-4 receptors. RGM-A and -C are plasma membrane bound, while RGM-B is generally microsomal in location. RGM-A and -B are associated with neurons, while RGM-C regulates skeletal muscle and hepatocyte function.
Long Name
Repulsive Guidance Molecule B
Alternate Names
Dragon, RGMB
Gene Symbol
RGMB
Additional RGM-B Products
Product Documents for RGM-B Antibody (398528) [FITC]
Product Specific Notices for RGM-B Antibody (398528) [FITC]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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