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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Janelia Fluor 525

Antibody Source

Monoclonal Mouse IgG2B Clone # 351713

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

E. coli-derived recombinant human Relaxin-1
Lys26-Cys185
Accession # P04808

Specificity

Detects the precursor form of human Relaxin-1 in direct ELISAs and Western blots. Does not detect mature Relaxin-1 heterodimer. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Relaxin-2 precursor or rhRelaxin-3 precursor is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Relaxin-1 Antibody (351713) [Janelia Fluor® 525]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Relaxin-1

Relaxin-1 is a protein that is 185 amino acids long, weighs approximately 21 kDa, and has a shorter isoform that is 117 amino acids long and weighs approximately 13 kDa. Relaxin-1 functions as an ovarian hormone that combines with estrogen to produce birth canal dialation as well as remodels connective tissues during pregnancy. Current studies are being done on diseases and disorders relating to this protein including diabetes mellitus, germ cell cancer, pulmonary function, neuroendocrine tumors, cryptorchidism, hepatitis, thyroiditis, breast cancer, hepatitis, hypertension, and cerebritis. Relaxin-1 has also been shown to have interactions with AR, RNF6, and RXFP1 in pathways such as the relaxin, PKC activation, myometrial relaxation and contraction, and androgen receptor signaling pathways.

Alternate Names

H1, Relaxin1, RLN1, RLXH1

Gene Symbol

RLN1

Additional Relaxin-1 Products

Product Documents for Relaxin-1 Antibody (351713) [Janelia Fluor® 525]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Relaxin-1 Antibody (351713) [Janelia Fluor® 525]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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