Rat IFN-beta Antibody
R&D Systems, part of Bio-Techne | Catalog # 33400-1
Key Product Details
Species Reactivity
Validated:
Cited:
Applications
Validated:
Cited:
Label
Antibody Source
Product Specifications
Immunogen
Specificity
Clonality
Host
Isotype
Applications for Rat IFN-beta Antibody
Neutralization
Formulation, Preparation, and Storage
Purification
Reconstitution
Formulation
Shipping
Stability & Storage
Background: IFN-beta
IFN-beta (Interferon-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.
References
- Ruuls, S.R. et al. (1996) J. Immunol. 157: 5721;
- Zou, L.P. et al. 1999. Neuroscience Res. 56: 123
Long Name
Alternate Names
Gene Symbol
Additional IFN-beta Products
Product Documents for Rat IFN-beta Antibody
Product Specific Notices for Rat IFN-beta Antibody
For research use only