PTP mu/PTPRM Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB110-39013

Novus Biologicals, part of Bio-Techne
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NB110-39013
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Equine, Hamster, Rabbit

Predicted:

Monkey (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all PTP mu/PTPRM Antibodies »

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from internal region of human PPTP mu/PTPRM.

Epitope

Internal region

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (94%).

Specificity

Human PTPRM. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for PTP mu/PTPRM Antibody - BSA Free

Immunohistochemistry-Paraffin: PTP mu/PTPRM Antibody - BSA Free [NB110-39013]

Immunohistochemistry-Paraffin: PTP mu/PTPRM Antibody - BSA Free [NB110-39013]

Immunohistochemistry-Paraffin: PTP mu/PTPRM Antibody - BSA Free [NB110-39013] - Analysis of anti-PTPRM antibody with human retina at concentration 15 ug/ml.

Applications for PTP mu/PTPRM Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

15 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: PTP mu/PTPRM

PTP mu, a R2A receptor protein tyrosine phosphatase, is composed of an extracellular segment containing a MAM domain, an immunoglobulin domain and four fibronectin type III repeats, a transmembrane segment, and two intracellular protein phosphatase domains. PTP mu has been shown to affect cell-cell aggregation, regulate cardiac myocyte Kv1.5 channel expression, and promote neurite outgrowth of retinal ganglion cells. The human PTP mu gene is localized on chromosome 18pter-q11, a region with frequent abnormalities implicated in human cancer. PTP mu may be important in responses to pathological conditions associated with the loss of cell-cell interactions in the heart.

Long Name

Protein Tyrosine Phosphatase Receptor-type M

Alternate Names

PTPRL1, PTPRM, R-PTP-mu

Entrez Gene IDs

5797 (Human)

Gene Symbol

PTPRM

UniProt

P28827

Additional PTP mu/PTPRM Products

Product Documents for PTP mu/PTPRM Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTP mu/PTPRM Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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