Proteasome 20S alpha 6 Antibody (24GB13270)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-51903

Novus Biologicals, part of Bio-Techne
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NBP3-51903-20ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Knockdown Validated

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 24GB13270

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Proteasome 20S alpha 6 Antibodies »

Product Specifications

Immunogen

Recombinant protein of human Proteasome 20S alpha 6 (Uniprot: P60900)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Applications for Proteasome 20S alpha 6 Antibody (24GB13270)

Application
Recommended Usage

Knockdown Validated

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Proteasome 20S alpha 6

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.

Long Name

Proteasome subunit alpha type-6

Alternate Names

p27K, PROS-27, PROS27, PSMA6

Gene Symbol

PSMA6

Additional Proteasome 20S alpha 6 Products

Product Documents for Proteasome 20S alpha 6 Antibody (24GB13270)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Proteasome 20S alpha 6 Antibody (24GB13270)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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