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Proprotein Convertase 1/PCSK1 Antibody [Alexa Fluor™ Plus 680]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98925AFP680

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NBP2-98925AFP680
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Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Alexa Fluor Plus 680 (Excitation = 687 nm, Emission = 704 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Produced in rabbits immunized with purified, recombinant Human Proprotein Convertase 1/PCSK1 (Accession#: NP_000430.3; Met 1-Arg 617)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for Proprotein Convertase 1/PCSK1 Antibody [Alexa Fluor™ Plus 680]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Proprotein Convertase 1/PCSK1

Proprotein Convertase 1, also known as PCSK1, PC1 or PC3, is a serine protease in the Furin family. Autocatalytic processing results in the removal of the pro peptide as well as a region from the C-terminus, which leads to the production of the most active 66 kDa form. PCSK1 is predominantly expressed in endocrine and neural cells and is stored in dense-core secretory vesicles, PCSK1 processes several endocrine and neural prohormones, including opiomelanocortin, somatostatin, enkephalin, insulin, dynorphin, and thyrotropin-releasing hormone. PCSK1 mutations are assiciated with obesity and impaired prohormone processing.

 

Alternate Names

NEC1, PCSK1

Gene Symbol

PCSK1

Additional Proprotein Convertase 1/PCSK1 Products

Product Documents for Proprotein Convertase 1/PCSK1 Antibody [Alexa Fluor™ Plus 680]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Proprotein Convertase 1/PCSK1 Antibody [Alexa Fluor™ Plus 680]



This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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