Key Product Details

Species Reactivity

Mouse

Applications

ELISA Capture (Matched Antibody Pair), ELISA Detection (Matched Antibody Pair), ELISA Standard (Matched Pair), Western Blot

Label

DyLight 594 (Excitation = 593 nm, Emission = 618 nm)

Antibody Source

Polyclonal Goat IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PRDC/GREM2 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse PRDC
Arg22-Gln168
Accession # O88273

Specificity

Detects mouse PRDC in ELISAs and Western blots. In sandwich ELISAs, less than 0.1% cross-reactivity with recombinant mouse (rm) Cerberus, rmGremlin, rmDAN, recombinant human (rh) COCO, rhGremlin, and rmBMP-4 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for PRDC/GREM2 Antibody [DyLight 594]

Application
Recommended Usage

ELISA Capture (Matched Antibody Pair)

Optimal dilutions of this antibody should be experimentally determined.

ELISA Detection (Matched Antibody Pair)

Optimal dilutions of this antibody should be experimentally determined.

ELISA Standard (Matched Pair)

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PRDC/GREM2

GREM2, also known as Gremlin-2, is a 168 amino acid that is 19 kDa, belongs to the DAN family, plays a role in the inhibition of the activity of BMP2 and BMP4 in a dose-dependent manner, and as an antagonist of BMP, it may play a role in regulating organogenesis, body patterning, and tissue differentiation. Current research is being performed on several diseases and disorders including astigmatism, myopia, accommodative esotropia, keratoconus, intraocular retinoblastoma, scimitar syndrome, swine influenza, influenza, norrie disease, and multiple sclerosis. The GREM2 protein is known to have an interaction with BMP4, BMP2, CER1, NOG, and FSTL1 in signal transduction and signaling by BMP pathways.

Long Name

Protein Related to DAN and Cerberus/Gremlin-2

Alternate Names

CKTSF1B2, DAND3, GREM2

Gene Symbol

GREM2

Additional PRDC/GREM2 Products

Product Documents for PRDC/GREM2 Antibody [DyLight 594]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PRDC/GREM2 Antibody [DyLight 594]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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