PRCC Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-46902

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PRCC Antibodies »

Product Specifications

Immunogen

papillary renal cell carcinoma(translocation-associated). (Uniprot# Q92733)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

66 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PRCC Antibody - BSA Free

PRCC Antibody - BSA Free

Western Blot: PRCC Antibody - BSA Free [NBP3-46902] -

Western Blot: PRCC Antibody - BSA Free [NBP3-46902] - HeLa cells were subjected to SDS PAGE followed by western blot with (PRCC antibody) at dilution of 1:500

Applications for PRCC Antibody - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PRCC

In a subset of papillary renal cell carcinomas, a t(X;1)(p11;q21) chromosome translocation has been repeatedly reported and is thought to be the cause of the cancer. As a result of the translocation, the transcription factor TFE3 on the X chromosome becomes fused to the PRCC (papillary renal cell carcinoma translocation-associated) gene on chromosome 1. The fused gene results in the fusion of N-terminal proline-rich region of the protein encoded by this gene to the entire TFE3 protein. This protein has been shown to interact with the mitotic checkpoint protein MAD2B, which suggests that the dominant-negative effect of the fusion protein with TFE3 may lead to a mitotic checkpoint defect.

Alternate Names

MGC17178, papillary renal cell carcinoma (translocation-associated), Papillary renal cell carcinoma translocation-associated gene protein, proline-rich protein PRCC, RCCP1MGC4723, TPRC

Gene Symbol

PRCC

Additional PRCC Products

Product Documents for PRCC Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PRCC Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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