PON2 encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Long Name

Paraoxonase 2

Alternate Names

A-esterase 2, Serum Aryldialkylphosphatase 2

Gene Symbol

PON2

Additional PON2 Products

Product Documents for PON2 Antibody [Janelia Fluor® 646]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for PON2 Antibody [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

PON2 Antibody [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # AF4344J

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all PON2 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Applications for PON2 Antibody [Janelia Fluor® 646]

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: PON2